Ototopical drops containing a novel antibacterial synthetic peptide: Safety and efficacy in adults with chronic suppurative otitis media.

OBJECTIVE:Chronic suppurative otitis media (CSOM) is a chronic infectious disease with worldwide prevalence that causes hearing loss and decreased quality of life. As current (antibiotic) treatments often unsuccessful and antibiotic resistance is emerging, alternative agents and/or strategies are ur...

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Main Authors: Nanno F A W Peek, Marja J Nell, Ronald Brand, Thekla Jansen-Werkhoven, Ewoud J van Hoogdalem, Ruud Verrijk, Marcel J Vonk, Amon R Wafelman, A Rob P M Valentijn, Johan H M Frijns, Pieter S Hiemstra, Jan W Drijfhout, Peter H Nibbering, Jan J Grote
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231573