Microphysiological system for heart tissue - going from 2D to 3D culture

Recently, we could demonstrate positive effects of microfluidic cultivation conditions on maturation of cardiomyocytes derived from human induced pluripotent stem cells (iPS-CMs) in a 2D model. However, 3D cell culture models are much closer to physiological conditions. Combined with microfluidics,...

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Bibliographic Details
Main Authors: Busek Mathias, Schubert Mario, Guan Kaomei, Sonntag Frank, Schmieder Florian, Marschner Uwe, Richter Andreas
Format: Article
Language:English
Published: De Gruyter 2019-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2019-0068