Kidney-induced systemic tolerance of heart allografts in mice

Kidney-induced systemic tolerance of heart allografts in mice

In swine and nonhuman primates, kidney allografts can induce tolerance of heart allografts, leading to their long-term, immunosuppression-free survival. We refer to this phenomenon as kidney-induced cardiac allograft tolerance (KICAT). In this study, we have developed a murine model for KICAT to det...

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Bibliographic Details
Main Authors: Chao Yang, Jifu Ge, Ivy Rosales, Qing Yuan, Edward Szuter, Ellen Acheampong, Paul S. Russell, Joren C. Madsen, Robert B. Colvin, Alessandro Alessandrini
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-09-01
Series:JCI Insight
Subjects:
Transplantation
Online Access:https://doi.org/10.1172/jci.insight.139331

Internet

https://doi.org/10.1172/jci.insight.139331

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