Comparison of piperacillin plasma concentrations in a prospective randomised trial of extended infusion versus intermittent bolus of piperacillin/tazobactam in paediatric patients

Comparison of piperacillin plasma concentrations in a prospective randomised trial of extended infusion versus intermittent bolus of piperacillin/tazobactam in paediatric patients

Objectives: To be effective, piperacillin/tazobactam (PTZ) unbound plasma levels need to be above the minimum inhibitory concentration (MIC) at least 50% of the time between dosing intervals (50% fT>MIC). This study aimed to compare the plasma piperacillin concentrations at the mid-dosing interva...

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Bibliographic Details
Main Authors: Tatchanapong Chongcharoenyanon, Noppadol Wacharachaisurapol, Suvaporn Anugulruengkitt, Passara Maimongkol, Orawan Anunsittichai, Jiratchaya Sophonphan, Tanittha Chatsuwan, Thanyawee Puthanakit
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:International Journal of Infectious Diseases
Subjects:
Multidrug-resistant organisms
Piperacillin
Extended infusion
Paediatrics
Therapeutic drug monitoring
Online Access:http://www.sciencedirect.com/science/article/pii/S120197122100446X

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http://www.sciencedirect.com/science/article/pii/S120197122100446X

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