A Saccharomyces cerevisiae assay system to investigate ligand/AdipoR1 interactions that lead to cellular signaling.

Adiponectin is a mammalian hormone that exerts anti-diabetic, anti-cancer and cardioprotective effects through interaction with its major ubiquitously expressed plasma membrane localized receptors, AdipoR1 and AdipoR2. Here, we report a Saccharomyces cerevisiae based method for investigating agonist...

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Bibliographic Details
Main Authors: Mustapha Aouida, Kangchang Kim, Abdul Rajjak Shaikh, Jose M Pardo, Jörg Eppinger, Dae-Jin Yun, Ray A Bressan, Meena L Narasimhan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23762377/?tool=EBI