A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human BeingsSummary

Background & Aims: Disturbances of the enterohepatic circulation of bile acids (BAs) are seen in a number of clinically important conditions, including metabolic disorders, hepatic impairment, diarrhea, and gallstone disease. To facilitate the exploration of underlying pathogenic mechanisms,...

Full description

Bibliographic Details
Main Authors: Veronika Voronova, Victor Sokolov, Amani Al-Khaifi, Sara Straniero, Chanchal Kumar, Kirill Peskov, Gabriel Helmlinger, Mats Rudling, Bo Angelin
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X20300266