The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review

The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review

Abstract FAK is a tyrosine kinase overexpressed in cancer cells and plays an important role in the progression of tumors to a malignant phenotype. Except for its typical role as a cytoplasmic kinase downstream of integrin and growth factor receptor signaling, related studies have shown new aspects o...

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Bibliographic Details
Main Authors: Jin Zhou, Qian Yi, Liling Tang
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Nuclear FAK
Cancer
Transcription factors
Gene expression
Inhibitors
Online Access:http://link.springer.com/article/10.1186/s13046-019-1265-1

Internet

http://link.springer.com/article/10.1186/s13046-019-1265-1

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