Nox4 is a Target for Tuberin Deficiency Syndrome

Nox4 is a Target for Tuberin Deficiency Syndrome

Abstract The mechanism by which TSC2 inactivation or deficiency contributes to the pathology of tuberous sclerosis complex (TSC) is not fully clear. We show that renal angiomyolipomas from TSC patients and kidney cortex from Tsc2+/− mice exhibit elevated levels of reactive oxygen species (ROS). Down...

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Bibliographic Details
Main Authors: Qian Shi, Suryavathi Viswanadhapalli, William E. Friedrichs, Chakradhar Velagapudi, Cédric Szyndralewiez, Shweta Bansal, Manzoor A. Bhat, Goutam Ghosh Choudhury, Hanna E. Abboud
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21838-4

Internet

https://doi.org/10.1038/s41598-018-21838-4

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