Association with CYP2C19 polymorphisms and Clopidogrel in treatment of elderly stroke patients

Abstract Background Clopidogrel is an antiplatelet drug used in the treatment of ischemic stroke. Safety and efficacy of clopidogrel has been confirmed in CAPRIE, PRoFESS trials. However, these studies focused on patients aged less than 75 years. CYP2C19 polymorphisms resulted in individual differen...

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Bibliographic Details
Main Authors: Changqing Li, Weihua Jia, Jian Li, Fangfei Li, Jing Ma, Lichun Zhou
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Neurology
Subjects:
Online Access:https://doi.org/10.1186/s12883-021-02127-6