Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

Population structure can bias the results of genetic and epidemiological analysis. Here, Haworth et al. report that fine-scale structure is detectable in apparently homogeneous samples such as ALSPAC when measured very precisely, and remains detectable in UK Biobank despite conventional approaches t...

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Bibliographic Details
Main Authors: Simon Haworth, Ruth Mitchell, Laura Corbin, Kaitlin H. Wade, Tom Dudding, Ashley Budu-Aggrey, David Carslake, Gibran Hemani, Lavinia Paternoster, George Davey Smith, Neil Davies, Daniel J. Lawson, Nicholas J. Timpson
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-08219-1

Internet

https://doi.org/10.1038/s41467-018-08219-1

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