Design and analysis of CRISPR‐based underdominance toxin‐antidote gene drives

Design and analysis of CRISPR‐based underdominance toxin‐antidote gene drives

Abstract CRISPR gene drive systems offer a mechanism for transmitting a desirable transgene throughout a population for purposes ranging from vector‐borne disease control to invasive species suppression. In this simulation study, we assess the performance of several CRISPR‐based underdominance gene...

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Bibliographic Details
Main Authors: Jackson Champer, Samuel E. Champer, Isabel K. Kim, Andrew G. Clark, Philipp W. Messer
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Evolutionary Applications
Subjects:
confinement
CRISPR
gene drive
genetic engineering
modeling
toxin‐antidote
Online Access:https://doi.org/10.1111/eva.13180

Internet

https://doi.org/10.1111/eva.13180

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