TGF-β1 regulation of estrogen production in mature rat Leydig cells.

BACKGROUND: Besides androgens, estrogens produced in Leydig cells are also crucial for mammalian germ cell differentiation. Transforming growth factor-β1 (TGF-β1) is now known to have multiple effects on regulation of Leydig cell function. The objective of the present study is to determine whether T...

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Bibliographic Details
Main Authors: Man-Li Liu, Huan Wang, Zong-Ren Wang, Yu-Fen Zhang, Yan-Qiu Chen, Fang-Hong Zhu, Yuan-Qiang Zhang, Jing Ma, Zhen Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3612063?pdf=render