Sialidases affect the host cell adherence and epsilon toxin-induced cytotoxicity of Clostridium perfringens type D strain CN3718.

Clostridium perfringens type B or D isolates, which cause enterotoxemias or enteritis in livestock, produce epsilon toxin (ETX). ETX is exceptionally potent, earning it a listing as a CDC class B select toxin. Most C. perfringens strains also express up to three different sialidases, although the po...

Full description

Bibliographic Details
Main Authors: Jihong Li, Sameera Sayeed, Susan Robertson, Jianming Chen, Bruce A McClane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3234242?pdf=render