Dietary n-3 polyunsaturated fatty acids promote activation-induced cell death in Th1-polarized murine CD4+ T-cells

Dietary n-3 polyunsaturated fatty acids promote activation-induced cell death in Th1-polarized murine CD4+ T-cells

Dietary n-3 PUFAs have been shown to attenuate T-cell-mediated inflammation. To investigate whether dietary n-3 PUFAs promote activation-induced cell death (AICD) in CD4+ T-cells induced in vitro to a polarized T-helper1 (Th1) phenotype, C57BL/6 mice were fed diets containing either 5% corn oil (CO;...

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Bibliographic Details
Main Authors: Kirsten C. Switzer, Yang-Yi Fan, Naisyin Wang, David N. McMurray, Robert S. Chapkin
Format: Article
Language:English
Published: Elsevier 2004-08-01
Series:Journal of Lipid Research
Subjects:
docosahexaenoic acid
eicosapentaenoic acid
lipid rafts
interferon-γ
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520313109

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http://www.sciencedirect.com/science/article/pii/S0022227520313109

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