Comparative evaluation of Compritol® HD5 ATO with Sodium Stearyl Fumarate and PEG 6000 as amphiphilic, hydrodispersible pharmaceutical lubricants

Hydrophobic lubricants are commonly used to reduce the frictional forces generated during tableting but impart a hydrophobic film on the surface of the powder or granules. This negatively affects the performance properties of the resultant tablets by slowing disintegration and dissolution, which i...

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Bibliographic Details
Main Authors: Chhanda Kapadia, Ketkee Deshmukh
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2017-03-01
Series:Journal of Excipients and Food Chemicals
Subjects:
Online Access:https://jefc.scholasticahq.com/article/1329-comparative-evaluation-of-compritol-hd5-ato-with-sodium-stearyl-fumarate-and-peg-6000-as-amphiphilic-hydrodispersible-pharmaceutical-lubricants