Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression

Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression

Haploidentical Natural Killer (NK) cells have been shown as an effective and safe alternative for the treatment of haematological malignancies with poor prognosis for which traditional therapies are ineffective. In contrast to haematological cancer cells, that mainly grow as single suspension cells,...

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Bibliographic Details
Main Authors: Pilar M. Lanuza, Alan Vigueras, Sara Olivan, Anne C. Prats, Santiago Costas, Guillermo Llamazares, Diego Sanchez-Martinez, José María Ayuso, Luis Fernandez, Ignacio Ochoa, Julián Pardo
Format: Article
Language:English
Published: Taylor & Francis Group 2018-04-01
Series:OncoImmunology
Subjects:
allogeneic human primary natural killer cells
colorectal carcinoma
3d spheroids cultures
immunotherapy
natural killer cells activation
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1395123

Internet

http://dx.doi.org/10.1080/2162402X.2017.1395123

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