A Multiplex Thyroid-Specific Assay for Quantification of Circulating Thyroid Cell-Free RNA in Plasma of Thyroid Cancer Patients

A Multiplex Thyroid-Specific Assay for Quantification of Circulating Thyroid Cell-Free RNA in Plasma of Thyroid Cancer Patients

BackgroundThe standard of care for thyroid cancer management is thyroidectomy and adjuvant radioactive iodine (RAI). There is a paucity of clinical tool that quantifies residual thyroid volume reliably for precise adjuvant RAI dosing. Serum thyroglobulin (TG), tumour marker for thyroid cancer, takes...

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Bibliographic Details
Main Authors: Samantha Peiling Yang, Lian Chye Winston Koh, Kiat Whye Kong, Rajeev Parameswaran, Kelvin Siu Hoong Loke, Kee Yuan Ngiam, Wee Boon Tan, Thomas Loh, David Chee Eng Ng, Boon Cher Goh, Joanne Ngeow, E. Shyong Tai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Genetics
Subjects:
thyroid-specific transcripts
thyroglobulin antibody positivity
thyroid cancer surveillance follow-up
thyroglobulin assay
thyroid cancer recurrence
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.721832/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.721832/full

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