Modification of LDL with human secretory phospholipase A2 or sphingomyelinase promotes its arachidonic acid-releasing propensity

Modification of LDL with human secretory phospholipase A2 or sphingomyelinase promotes its arachidonic acid-releasing propensity

Oxidation and lipolytic remodeling of LDL are believed to stimulate LDL entrapment in the arterial wall, expanding the inflammatory response and promoting atherosclerosis. However, the cellular responses and molecular mechanisms underlying the atherogenic effects of lipolytically modified LDL are in...

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Bibliographic Details
Main Authors: Janne Oestvang, Dominique Bonnefont-Rousselot, Ewa Ninio, Jukka K. Hakala, Berit Johansen, Marit W. Anthonsen
Format: Article
Language:English
Published: Elsevier 2004-05-01
Series:Journal of Lipid Research
Subjects:
low density lipoprotein remodeling
inflammation
atherosclerosis
monocytes
oleic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318228

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http://www.sciencedirect.com/science/article/pii/S0022227520318228

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