Modification of LDL with human secretory phospholipase A2 or sphingomyelinase promotes its arachidonic acid-releasing propensity
Oxidation and lipolytic remodeling of LDL are believed to stimulate LDL entrapment in the arterial wall, expanding the inflammatory response and promoting atherosclerosis. However, the cellular responses and molecular mechanisms underlying the atherogenic effects of lipolytically modified LDL are in...
Main Authors: | Janne Oestvang, Dominique Bonnefont-Rousselot, Ewa Ninio, Jukka K. Hakala, Berit Johansen, Marit W. Anthonsen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2004-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520318228 |
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