White Matter Regions With Low Microstructure in Young Adults Spatially Coincide With White Matter Hyperintensities in Older Adults

White Matter Regions With Low Microstructure in Young Adults Spatially Coincide With White Matter Hyperintensities in Older Adults

Microstructural and macrostructural white matter damage occurs frequently with aging, is associated with negative health outcomes, and can be imaged non-invasively as fractional anisotropy (FA) and white matter hyperintensities (WMH), respectively. The extent to which diminished microstructure prece...

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Bibliographic Details
Main Authors: Patrick J. Lao, Robert S. Vorburger, Atul Narkhede, Yunglin Gazes, Kay C. Igwe, Juliet Colón, Erica Amarante, Vanessa A. Guzman, Briana S. Last, Christian Habeck, Yaakov Stern, Adam M. Brickman
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
white matter microstructure
white matter macrostructure
diffusion-weighted imaging
white matter hyperintensity
across the lifespan
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00345/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2019.00345/full

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