Genomic Instability Is an Early Event in Aluminium-Induced Tumorigenesis

Genomic Instability Is an Early Event in Aluminium-Induced Tumorigenesis

Genomic instability is generally considered as a hallmark of tumorigenesis and a prerequisite condition for malignant transformation. Aluminium salts are suspected environmental carcinogens that transform mammary epithelial cells <i>in vitro</i> through unknown mechanisms. We report here...

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Bibliographic Details
Main Authors: Stefano J. Mandriota, Mirna Tenan, Adeline Nicolle, Julia D. Jankowska, Paolo Ferrari, Jean-Christophe Tille, Mary-Anne Durin, Catherine M. Green, Sebastien Tabruyn, Daniela Moralli, André-Pascal Sappino
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
aluminium
breast cancer
carcinogenesis
genomic instability
clastogens
Online Access:https://www.mdpi.com/1422-0067/21/23/9332

Internet

https://www.mdpi.com/1422-0067/21/23/9332

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