Transient ureteral obstruction prevents against kidney ischemia/reperfusion injury via hypoxia-inducible factor (HIF)-2α activation.

Transient ureteral obstruction prevents against kidney ischemia/reperfusion injury via hypoxia-inducible factor (HIF)-2α activation.

Although the protective effect of transient ureteral obstruction (UO) prior to ischemia on subsequent renal ischemia/reperfusion (I/R) injury has been documented, the underlying molecular mechanism remains to be understood. We showed in the current study that 24 h of UO led to renal tubular hypoxia...

Full description

Bibliographic Details
Main Authors: Shun Zhang, Cong-Hui Han, Xiao-Song Chen, Ming Zhang, Long-Mei Xu, Jian-Jun Zhang, Qiang Xia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3266244?pdf=render

Internet

http://europepmc.org/articles/PMC3266244?pdf=render

Similar Items