Relaxin and atrial natriuretic peptide pathways participate in the anti-fibrotic effect of a melon concentrate in spontaneously hypertensive rats

Relaxin and atrial natriuretic peptide pathways participate in the anti-fibrotic effect of a melon concentrate in spontaneously hypertensive rats

Background: In spontaneously hypertensive rats (SHR), a model of human essential hypertension, oxidative stress is involved in the development of cardiac hypertrophy and fibrosis associated with hypertension. Dietary supplementation with agents exhibiting antioxidant properties could have a benefici...

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Bibliographic Details
Main Authors: Julie Carillon, Audrey Gauthier, Sandy Barial, Michel Tournier, Nathalie Gayrard, Anne-Dominique Lajoix, Bernard Jover
Format: Article
Language:English
Published: Swedish Nutrition Foundation 2016-04-01
Series:Food & Nutrition Research
Subjects:
cardiomyocyte
endogenous antioxidant defense
fibrosis
oxidative stress
relaxin/insulin-like family peptide receptor 1
Online Access:http://www.foodandnutritionresearch.net/index.php/fnr/article/view/30985/45979

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http://www.foodandnutritionresearch.net/index.php/fnr/article/view/30985/45979

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