Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice

Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice

Summary: Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compared hippocampus biology and memory in mice subjected to 20% C...

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Bibliographic Details
Main Authors: Devin Wahl, Samantha M. Solon-Biet, Qiao-Ping Wang, Jibran A. Wali, Tamara Pulpitel, Ximonie Clark, David Raubenheimer, Alistair M. Senior, David A. Sinclair, Gregory J. Cooney, Rafael de Cabo, Victoria C. Cogger, Stephen J. Simpson, David G. Le Couteur
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718316747

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http://www.sciencedirect.com/science/article/pii/S2211124718316747

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