Nicotinamide nucleotide transhydrogenase (NNT) regulates mitochondrial ROS and endothelial dysfunction in response to angiotensin II

Endothelial dysfunction is a critical, initiating step in the development of hypertension (HTN) and mitochondrial reactive oxygen species (ROS) are important contributors to endothelial dysfunction. Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) in the...

Full description

Bibliographic Details
Main Authors: K.N. Shashanka Rao, Xinggui Shen, Sibile Pardue, David M. Krzywanski
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Redox Biology
Subjects:
NNT
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308557