Elevated dietary sodium intake exacerbates myocardial hypertrophy associated with cardiac-specific overproduction of angiotensin II

Introduction/hypothesis Cardiac hypertrophy is an independent risk factor predictive of cardiovascular disease and is significantly associated with morbidity and mortality. The mechanism by which angiotensin II (Ang II) and dietary sodium exert additive effects on the development of cardiac hypertro...

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Bibliographic Details
Main Authors: Enzo R Porrello, Catherine E Huggins, Claire L Curl, Andrea A Domenighetti, Thierry Pedrazzini, Leanne MD Delbridge, Trefor O Morgan
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2004-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2004.036