The Metabolites of the Dietary Flavonoid Quercetin Possess Potent Antithrombotic Activity, and Interact with Aspirin to Enhance Antiplatelet Effects

The Metabolites of the Dietary Flavonoid Quercetin Possess Potent Antithrombotic Activity, and Interact with Aspirin to Enhance Antiplatelet Effects

Quercetin, a dietary flavonoid, has been reported to possess antiplatelet activity. However, its extensive metabolism following ingestion has resulted in difficulty elucidating precise mechanisms of action. In this study, we aimed to characterize the antiplatelet mechanisms of two methylated metabol...

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Bibliographic Details
Main Authors: Alexander R. Stainer, Parvathy Sasikumar, Alexander P. Bye, Amanda J. Unsworth, Lisa M. Holbrook, Marcus Tindall, Julie A. Lovegrove, Jonathan M. Gibbins
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2019-07-01
Series:TH Open
Subjects:
platelets
quercetin
aspirin
flavonoids
thrombosis
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1694028

Internet

http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1694028

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