Investigating potential causal relationships between SNPs, DNA methylation and HDL

Abstract Using data on 680 patients from the GAW20 real data set, we conducted Mendelian randomization (MR) studies to explore the causal relationships between methylation levels at selected probes (cytosine-phosphate-guanine sites [CpGs]) and high-density lipoprotein (HDL) changes (ΔHDL) using sing...

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Bibliographic Details
Main Authors: Lai Jiang, Kaiqiong Zhao, Kathleen Klein, Angelo J. Canty, Karim Oualkacha, Celia M. T. Greenwood
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Proceedings
Online Access:http://link.springer.com/article/10.1186/s12919-018-0117-x