A genome-wide association study in mice reveals a role for Rhbdf2 in skeletal homeostasis

Abstract Low bone mass and an increased risk of fracture are predictors of osteoporosis. Individuals who share the same bone-mineral density (BMD) vary in their fracture risk, suggesting that microstructural architecture is an important determinant of skeletal strength. Here, we utilized the rich di...

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Bibliographic Details
Main Authors: Roei Levy, Clemence Levet, Keren Cohen, Matthew Freeman, Richard Mott, Fuad Iraqi, Yankel Gabet
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-60146-8