Active Human Complement Reduces the Zika Virus Load via Formation of the Membrane-Attack Complex

Active Human Complement Reduces the Zika Virus Load via Formation of the Membrane-Attack Complex

Although neglected in the past, the interest on Zika virus (ZIKV) raised dramatically in the last several years. The rapid spread of the virus in Latin America and the association of the infection with microcephaly in newborns or Guillain-Barré Syndrome in adults prompted the WHO to declare the ZIKV...

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Bibliographic Details
Main Authors: Britta Schiela, Sarah Bernklau, Zahra Malekshahi, Daniela Deutschmann, Iris Koske, Zoltan Banki, Nicole M. Thielens, Reinhard Würzner, Cornelia Speth, Guenter Weiss, Karin Stiasny, Eike Steinmann, Heribert Stoiber
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
complement
Zika virus
C1q
IgM
MAC
lysis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02177/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02177/full

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