Distinct Macrophage Fates after in vitro Infection with Different Species of Leishmania: Induction of Apoptosis by Leishmania (Leishmania) amazonensis, but Not by Leishmania (Viannia) guyanensis.

Leishmania is an intracellular parasite in vertebrate hosts, including man. During infection, amastigotes replicate inside macrophages and are transmitted to healthy cells, leading to amplification of the infection. Although transfer of amastigotes from infected to healthy cells is a crucial step th...

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Main Authors: Jarina Pena DaMata, Bárbara Pinheiro Mendes, Kátia Maciel-Lima, Cristiane Alves Silva Menezes, Walderez Ornelas Dutra, Lirlândia Pires Sousa, Maria Fátima Horta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4626090?pdf=render