Persistent STAT3 Activation in Colon Cancer Is Associated with Enhanced Cell Proliferation and Tumor Growth
Colorectal carcinoma (CRC) is a major cause of morbidity and mortality in Western countries. It has so far been molecularly defined mainly by alterations of the Wnt pathway. We show here for the first time that aberrant activities of the signal transducer and activator of transcription STAT3 active...
Main Authors: | Florian M. Corvinus, Carina Orth, Richard Moriggl, Svetlana A. Tsareva, Stefan Wagner, Edith B. Pfitzner, Daniela Baus, Roland Kaufman, Lukas A. Huber, Kurt Zatloukal, Hartmut Beug, Peter Öhlschläger, Alexander Schütz, Karl-Jürgen Halbhuber, Karlheinz Friedrich |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-06-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558605800752 |
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