Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional

Environmental and genetic risk factors affect the distal airway epithelium in idiopatic pulmonary fibrosis (IPF) but the role of the epithelium in IPF remains unclear. Here the authors show that pathologic activation of the ERBB-YAP axis induces dynamic and structural dysfunction in the distal airwa...

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Bibliographic Details
Main Authors: Ian T. Stancil, Jacob E. Michalski, Duncan Davis-Hall, Hong Wei Chu, Jin-Ah Park, Chelsea M. Magin, Ivana V. Yang, Bradford J. Smith, Evgenia Dobrinskikh, David A. Schwartz
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24853-8