The Activities of the Gelsolin Homology Domains of Flightless-I in Actin Dynamics

Flightless-I is a unique member of the gelsolin superfamily alloying six gelsolin homology domains and leucine-rich repeats. Flightless-I is an established regulator of the actin cytoskeleton, however, its biochemical activities in actin dynamics are still largely elusive. To better understand the b...

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Main Authors: Réka Pintér, Tamás Huber, Péter Bukovics, Péter Gaszler, Andrea Teréz Vig, Mónika Ágnes Tóth, Gabriella Gazsó-Gerhát, Dávid Farkas, Ede Migh, József Mihály, Beáta Bugyi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.575077/full