Tetherin restricts productive HIV-1 cell-to-cell transmission.

Tetherin restricts productive HIV-1 cell-to-cell transmission.

The IFN-inducible antiviral protein tetherin (or BST-2/CD317/HM1.24) impairs release of mature HIV-1 particles from infected cells. HIV-1 Vpu antagonizes the effect of tetherin. The fate of virions trapped at the cell surface remains poorly understood. Here, we asked whether tetherin impairs HIV cel...

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Bibliographic Details
Main Authors: Nicoletta Casartelli, Marion Sourisseau, Jerome Feldmann, Florence Guivel-Benhassine, Adeline Mallet, Anne-Geneviève Marcelin, John Guatelli, Olivier Schwartz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2887479?pdf=render

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http://europepmc.org/articles/PMC2887479?pdf=render

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