Atrophy rates in asymptomatic amyloidosis: implications for Alzheimer prevention trials.

Atrophy rates in asymptomatic amyloidosis: implications for Alzheimer prevention trials.

There is considerable interest in designing therapeutic studies of individuals at risk of Alzheimer disease (AD) to prevent the onset of symptoms. Cortical β-amyloid plaques, the first stage of AD pathology, can be detected in vivo using positron emission tomography (PET), and several studies have s...

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Bibliographic Details
Main Authors: K Abigail Andrews, Marc Modat, Kate E Macdonald, Tom Yeatman, M Jorge Cardoso, Kelvin K Leung, Josephine Barnes, Victor L Villemagne, Christopher C Rowe, Nick C Fox, Sebastien Ourselin, Jonathan M Schott, Australian Imaging Biomarkers, Lifestyle Flagship Study of Ageing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3599038?pdf=render

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http://europepmc.org/articles/PMC3599038?pdf=render

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