Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors

<p>Abstract</p> <p>Background</p> <p>The existence of large pores in the blood-tumor barrier (BTB) of malignant solid tumor microvasculature makes the blood-tumor barrier more permeable to macromolecules than the endothelial barrier of most normal tissue microvasculatur...

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Bibliographic Details
Main Authors: Griffiths Gary L, Aronova Maria A, Wilson Colin M, Sousa Alioscka A, Wu Haitao, Kanevsky Ariel S, Sarin Hemant, Leapman Richard D, Vo Howard Q
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/7/1/51