Selective Loss of Early Differentiated, Highly Functional PD1high CD4 T Cells with HIV Progression.
The role of PD-1 expression on CD4 T cells during HIV infection is not well understood. Here, we describe the differential expression of PD-1 in CD127high CD4 T cells within the early/intermediate differentiated (EI) (CD27highCD45RAlow) T cell population among uninfected and HIV-infected subjects, w...
Main Authors: | Robert M Paris, Constantinos Petrovas, Sara Ferrando-Martinez, Eirini Moysi, Kristin L Boswell, Eva Archer, Takuya Yamamoto, David Ambrozak, Joseph P Casazza, Richard Haubrich, Mark Connors, Julie Ake, Jerome H Kim, Richard A Koup |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4692060?pdf=render |
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