Bleomycin-Loaded pH-Sensitive Polymer–Lipid-Incorporated Liposomes for Cancer Chemotherapy

Bleomycin-Loaded pH-Sensitive Polymer–Lipid-Incorporated Liposomes for Cancer Chemotherapy

Cancer chemotherapeutic systems with high antitumor effects and less adverse effects are eagerly desired. Here, a pH-sensitive delivery system for bleomycin (BLM) was developed using egg yolk phosphatidylcholine liposomes modified with poly(ethylene glycol)-lipid (PEG-PE) for long circulation in the...

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Bibliographic Details
Main Authors: Eiji Yuba, Tomohiro Osaki, Misato Ono, Shinjae Park, Atsushi Harada, Masamichi Yamashita, Kazuo Azuma, Takeshi Tsuka, Norihiko Ito, Tomohiro Imagawa, Yoshiharu Okamoto
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Polymers
Subjects:
bleomycin
cancer
pH-sensitive liposome
polyglycidol
polymer–lipid
poly(ethylene glycol)
Online Access:http://www.mdpi.com/2073-4360/10/1/74

Internet

http://www.mdpi.com/2073-4360/10/1/74

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