Metabolic and cardiorespiratory effects of decreasing lung hyperinflation with budesonide/formoterol in COPD: a randomized, double-crossover, placebo-controlled, multicenter trial

Metabolic and cardiorespiratory effects of decreasing lung hyperinflation with budesonide/formoterol in COPD: a randomized, double-crossover, placebo-controlled, multicenter trial

Abstract Background Studies suggest that acute decreases in lung hyperinflation at rest improves cardiac function and increases lung vascular perfusion from decompression of a compromised heart. In those studies, changes in resting oxygen uptake induced by medications, an alternative explanation for...

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Bibliographic Details
Main Authors: Miguel J. Divo, Michael R. DePietro, John R. Horton, Cherie A. Maguire, Bartolome R. Celli
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Respiratory Research
Subjects:
Oxygen uptake
Cardiac output
Oxygen pulse
Stroke volume
Online Access:https://doi.org/10.1186/s12931-020-1288-3

Internet

https://doi.org/10.1186/s12931-020-1288-3

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