Induction of complement proteins in a mouse model for cerebral microvascular Aβ deposition

<p>Abstract</p> <p>The deposition of amyloid β-protein (Aβ) in cerebral vasculature, known as cerebral amyloid angiopathy (CAA), is a common pathological feature of Alzheimer's disease and related disorders. In familial forms of CAA single mutations in the Aβ peptide have been...

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Bibliographic Details
Main Authors: DeFilippis Kelly, Fan Rong, Van Nostrand William E
Format: Article
Language:English
Published: BMC 2007-09-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/4/1/22