Turnover of endogenous ceramide in cultured normal and Farber fibroblasts

De novo synthesis and turnover of endogenous ceramide in cultured skin fibroblasts from patients affected with Farber lipogranulomatosis were studied by biosynthetical labeling of cellular sphingolipids with [14C]serine. The cellular uptake of [14C]serine and incorporation into de novo synthesized c...

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Bibliographic Details
Main Authors: G van Echten-Deckert, A Klein, T Linke, T Heinemann, J Weisgerber, K Sandhoff
Format: Article
Language:English
Published: Elsevier 1997-12-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520300419