Stretch-Induced Biased Signaling in Angiotensin II Type 1 and Apelin Receptors for the Mediation of Cardiac Contractility and Hypertrophy

The myocardium has an intrinsic ability to sense and respond to mechanical load in order to adapt to physiological demands. Primary examples are the augmentation of myocardial contractility in response to increased ventricular filling caused by either increased venous return (Frank–Starling law) or...

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Bibliographic Details
Main Authors: Kinya Seo, Victoria N. Parikh, Euan A. Ashley
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Physiology
Subjects:
APJ
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00181/full