Persimmon tannin promoted macrophage reverse cholesterol transport through inhibiting ERK1/2 and activating PPARγ both in vitro and in vivo

Persimmon tannin promoted macrophage reverse cholesterol transport through inhibiting ERK1/2 and activating PPARγ both in vitro and in vivo

The purpose of this study was to investigate whether persimmon tannin is associated with cholesterol efflux and macrophage-reverse cholesterol transport (RCT). In J774A.1 macrophage cells, persimmon tannin could inhibit cellular cholesterol accumulation and promote 22-NBD-cholesterol efflux through...

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Bibliographic Details
Main Authors: Zhenzhen Ge, Mengying Zhang, Xiangyi Deng, Wei Zhu, Kaikai Li, Chunmei Li
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Journal of Functional Foods
Subjects:
Persimmon tannin
Macrophage RCT
Phosphorylation of ERK1/2
PPARγ
Cholesterol efflux
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617305352

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http://www.sciencedirect.com/science/article/pii/S1756464617305352

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