Resveratrol, a SIRT1 Activator, Ameliorates MK-801-Induced Cognitive and Motor Impairments in a Neonatal Rat Model of Schizophrenia

Resveratrol, a SIRT1 Activator, Ameliorates MK-801-Induced Cognitive and Motor Impairments in a Neonatal Rat Model of Schizophrenia

BackgroundIn neonatal rats, MK-801 treatment generates schizophrenia-like symptoms. Resveratrol (RSV) is a phenolic compound and a potent neuroprotective agent. This research aimed to illustrate the effect of RSV on the amelioration of MK-801-induced cognitive and motor impairments in a neonatal rat...

Full description

Bibliographic Details
Main Authors: Juan Niu, Yuquan Cao, Yongjuan Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Psychiatry
Subjects:
resveratrol
MK-801
silent information regulator 1
brain derived neurotrophic factor
schizophrenia
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2020.00716/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2020.00716/full

Similar Items