The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer’s Disease

The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer’s Disease

Alzheimer’s Disease (AD) features the accumulation of β-amyloid and Tau aggregates, which deposit as extracellular plaques and intracellular neurofibrillary tangles (NFTs), respectively. Neuronal Tau aggregates may appear early in life, in the absence of clinical symptoms. This occurs in the brainst...

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Bibliographic Details
Main Authors: Filippo S. Giorgi, Larisa Ryskalin, Riccardo Ruffoli, Francesca Biagioni, Fiona Limanaqi, Michela Ferrucci, Carla L. Busceti, Ubaldo Bonuccelli, Francesco Fornai
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Neuroanatomy
Subjects:
neurofibrillary tangles
basal forebrain nuclei
phospho-Tau
amyloid
mild cognitive impairment
pre-clinical AD
Online Access:http://journal.frontiersin.org/article/10.3389/fnana.2017.00080/full

Internet

http://journal.frontiersin.org/article/10.3389/fnana.2017.00080/full

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