Dynamic Expression of Lgr6 in the Developing and Mature Mouse Cochlea

Dynamic Expression of Lgr6 in the Developing and Mature Mouse Cochlea

The Wnt/β-catenin signaling pathway plays important roles in mammalian inner ear development. Lgr5, one of the downstream target genes of the Wnt/β-catenin signaling pathway, has been reported to be a marker for inner ear hair cell progenitors. Lgr6 shares approximately 50% sequence homology with Lg...

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Bibliographic Details
Main Authors: Yanping eZhang, Yan eChen, Wenli eNi, Luo eGuo, Xiaoling eLu, Liman eLiu, Wen eLi, Shan eSun, Lei eWang, Huawei eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Regeneration
Wnt
Hair cells
Hair cell progenitor
Lgr6
inner pillar cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00165/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00165/full

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