Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

Oral ulcerations are sores of the mucous membrane of the mouth and highly prevalent in the population. Here, in a genome-wide association study, the authors identify 97 loci associated with mouth ulcers highlighting genes involved in T cell-mediated immunity and TH1 responses.

Bibliographic Details
Main Authors: Tom Dudding, Simon Haworth, Penelope A. Lind, J. Fah Sathirapongsasuti, 23andMe Research Team, Joyce Y. Tung, Ruth Mitchell, Lucía Colodro-Conde, Sarah E. Medland, Scott Gordon, Benjamin Elsworth, Lavinia Paternoster, Paul W. Franks, Steven J. Thomas, Nicholas G. Martin, Nicholas J. Timpson
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08923-6

Internet

https://doi.org/10.1038/s41467-019-08923-6

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