BFAST: an alignment tool for large scale genome resequencing.

BACKGROUND:The new generation of massively parallel DNA sequencers, combined with the challenge of whole human genome resequencing, result in the need for rapid and accurate alignment of billions of short DNA sequence reads to a large reference genome. Speed is obviously of great importance, but equ...

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Bibliographic Details
Main Authors: Nils Homer, Barry Merriman, Stanley F Nelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2770639?pdf=render