Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis

Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis

Abstract Background A decrease in blood lactate levels (Lac) >10% during the first hours of resuscitation in sepsis is associated with better outcomes, but the mechanisms are unclear. Our objective was to investigate the relationship between the time course of Lac, inflammatory response, and mito...

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Bibliographic Details
Main Authors: Thiago Domingos Corrêa, Adriano José Pereira, Sebastian Brandt, Madhusudanarao Vuda, Siamak Djafarzadeh, Jukka Takala, Stephan Mathias Jakob
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Critical Care
Subjects:
Sepsis
Septic shock
Lactate kinetics
Mitochondrial respiration
Resuscitation
Cytokines
Online Access:http://link.springer.com/article/10.1186/s13054-017-1691-4

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http://link.springer.com/article/10.1186/s13054-017-1691-4

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